MitogenDx’s COVID-19 (SARS-CoV-2) Antibody Serology Test for Dired Blood Spots (DBS) detects antibodies (IgG) against COVID-19 Spike Protein (S1 subunit), COVID-19 Nucleocapsid Protein, and COVID-19 Receptor Binding Domain from a DBS sample. A positive test indicates exposure to the SARS-CoV2 virus and an immune response to SARS-CoV2 vaccines. Results provided show semi-quantitative levels of antibodies against these three critical COVID-19 / SARS-CoV-2 antigens (targets) and generates a final report on COVID-19 immunity.
With this COVID-19 Antibody Serology Test accommodating dried blood spot testing, a new level of convenience and value is achieved. Rather than going to a laboratory for a blood draw or contracting a phlebotomist, you receive a lancet and a blood spot card. In the comfort of your home, simply follow the instructions on using the lancet to spot a drop of blood onto a collection card. Using a lancet to create a dried blood spot is not only considered to be relatively pain-free, it also is more convenient, more cost-effective, and entirely avoids the stress and pain associated with a venipuncture blood draw. With this service offered by MitogenDx, getting your results is not only significantly less expensive than the test price offered by other laboratories, it is a fraction of the total cost that involves standard venipuncture blood collection.
Upon receiving your returned dried blood spot (DBS), MitogenDx processes the DBS to elute the preserved antibodies. Your blood is then tested for antibodies (IgG) against COVID-19 Spike Protein (S1 subunit), COVID-19 Nucleocapsid Protein, and COVID-19 Receptor Binding Domain to indicate your level of immunity against COVID-19.
What is a DBS sample collection kit?
This test includes a dried blood spot (DBS) sample collection kit that is mailed to the customer / user. The test kit consists of a lancet, an alcohol wipe, a blood spot card, a barcoded tube for storing the DBS, instructions for use, and return shipping. When multiple quantities are ordered for this test from a single customer address / location, the number of DBS sample collection kits will match the quantity ordered and each barcoded tube will be designated to a specific person.
What is a lancet?
Unlike large-gauge blood collection needles that are used by a phlebotomist to collect millilitres of blood from within a vein, a lancet is a small device that is used to prick a finger to allow for micro blood collection from microscopic blood capillaries. The finger prick is tiny and shallow (~1.5mm or 0.06”) and the lancet action and automatic retraction is completed in milliseconds. When a lancet is used on the side of a finger where fewer nerve endings reside the user merely feels the pressure of the lancet collar and virtually no pain.
What is an antibody serology test?
One of the most dynamic features of your body’s immune system is its ability to recognize something foreign (such as a virus or unwanted bacteria) and to develop a corresponding targeted attack. Antibodies (also known as immunoglobulins) are robust proteins that are uniquely designed and produced by your body’s immune system that seek out foreign targets. When an antibody finds its target it acts as a homing beacon for immune cells to initiate the destruction and removal of the foreign substance. In the case of a viral infection or vaccination, your body will raise an immune response against the virus (or vaccine) which in-turn inhibits the virus’s ability to replicate and cause harm to your body. There are a number of different antibody/immunoglobulin classes that have different features and functions. The most common antibody class that is involved with long-term immunity is IgG. An antibody serology test is a test completed on a blood sample to detect the presence of specific antibodies. In the case of Eve Technologies’ COVID-19 Antibody Serology Test, IgG antibodies that are required for COVID-19 immunity (antibodies against COVID-19 Spike Protein (S1 subunit), COVID-19 Nucleocapsid Protein, and COVID-19 Receptor Binding Domain) are independently detected giving a semi-quantifiable result.
Why is antibody testing important?
Knowing if you have antibodies against COVID-19 not only indicates if you’ve had an infection in the past, it also gives indications towards an active infection, the success of immunization, and the total scope of your immunity against COVID-19. The immunity gained through antibody production is not guaranteed to be long-term. Few vaccines and the resulting antibodies and the cells programmed to produce specific antibodies (B-cells) remain effective for life. Some have an efficacy for a number of years, and others are only viable for a number of months or even weeks. Although antibodies against COVID-19 likely provide some immunity (dependent on antibody levels and the presence of neutralizing antibodies that inactivate the virus) there is currently not enough evidence to know how long the antibodies last or to what extent past infection with the virus helps protect you from getting another infection. Therefore it is important for individuals, employers, and society in general to know what your COVID antibody status is today and in the future.