Autoimmune Myopathy / Myositis Panel PLUS

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ANTIGENS / BIOMARKERS

Anti-Jo-1, Mi2-α, Mi2-β, MDA5, NXP2, TIF1γ, PL7, PL12, PM/Scl75, PM/Scl100, Ku, SRP, EJ, OJ, Ro52/TRIM21, SAE1, HMGCR, NT5C1A/Mup44

SKU / TEST CODE

MYO+

PROCEDURE / TECHNIQUE

Line Immunoassay (LIA), CIA

REFERENCE RANGE

Qualitative (SI :Signal Intensity) • Negative <10 SI • Weak Positive 11-29 SI • Medium Positive 30-89 SI • High positive >90 SI

SENSITIVITY / SPECIFICITY

TBD

CLINICAL ASSOCIATIONS

Mitogen’s Autoimmune Myopathy / Myositis Profile PLUS assay is an autoimmune diagnostic test that detects autoantibodies in a comprehensive antigen panel that relates to autoimmune myopathy and myositis. The sample will be tested for autoantibodies to the following myositis-related and myositis-specific antigens: Mi-2, Ku, PM/Scl, Jo-1, PL-7, PL-12, EJ, OJ, SRP, Ro-52/TRIM21, NT5c1A/Mup44.

Reference: Y. Gonzalez-Bello, I. Garcia-Valladares, I. V. Reyes-Perez, et al.. Myositis-Specific Antibodies and Myositis-Associated Antibodies in Patients With Idiopathic Inflammatory Myopathies From the PANLAR Myositis Study Group. J Clin Rheumatol. EPub ahead of print:10, 2020.