HEp2 IFA Titer and Pattern & Anti‐CENP A + B, Topo‐I/Scl‐70, RNA polymerase III, fibrillarin/U3RNP, Th/To/hPOP1, Ku, PDGFR, Ro52/TRIM21, PM/Scl‐75, PM/Scl‐100, NOR90/Hubf
5-7 Days
NAP
Immunofluorescence Assay (IFA), Line Immunoassay (LIA)
Qualitative (SI :Signal Intensity) • Negative <10 SI • Weak Positive 11-29 SI • Medium Positive 30-89 SI • High positive >90 SI
TBD
Mitogen’s Nucleolar Autoantibody Profile is an autoimmune diagnostic test that identifies anti-nucleolar antibodies that are often a challenge to detect and identify by HEp-2 IFA (AC-1, 8, 9, 10). Historically, anti-nucleolar antibodies were primarily associated with scleroderma. However, they are seen in a wide variety of other conditions.
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