Sjögren Syndrome / Disease Panel
ANTIGENS / BIOMARKERS
Anti-Sm, U1RNP, Ro52/TRIM21, SSA/Ro60, SSB/La, PCNA, dsDNA, Ku, Ribosomal-P, Chromatin
SKU / TEST CODE
SJS
PROCEDURE / TECHNIQUE
Line Immunoassay (LIA)
REFERENCE RANGE
Qualitative (SI :Signal Intensity) • Negative <10 SI • Weak Positive 11-29 SI • Medium Positive 30-89 SI • High positive >90 SI
SENSITIVITY / SPECIFICITY
TBD
CLINICAL ASSOCIATIONS
Mitogen’s Sjögren Syndrome Profile is an autoimmune diagnostic test for Sjögren syndrome-related autoantibodies directed to SS-A/Ro60, SS-B/La, and Ro52/TRIM21. The presence of these autoantibodies are serological features of Sjögren syndrome.
Reference: E. Martin-Naresa and G. Hernandez-Molinaa. Novel autoantibodies in Sjögren’s Syndrome: A comprehensive review. Autoimmun.Rev. 18:192-198, 2019.
RELEVANT DISEASES
- Anti-glutamate receptor encephalitis (type NMDA)
- Arthritis
- Arthritis (Juvenile arthritis / Juvenile idiopathic arthritis)
- Arthritis (Rheumatoid Arthritis)
- Asthma
- Autoimmune liver diseases
- Autoimmune mucocutaneous blistering diseases
- Chorea
- Encephalitis
- Guillain-Barré syndrome
- Interstitial lung disease (ILD)
- Limbic encephalitis (autoinflammatory)
- Lupus, Systemic lupus erythematous (SLE)
- Mixed connective tissue disease
- Multifocal motor neuropathy (MMN)
- Primary Membranous nephropathy (pMN): aka primary membranous glomerulonephritis (pMGN) and idiopathic membranous nephropathy (IMN)
- Primary biliary cholangitis
- Rheumatoid Arthritis
- Scleroderma / systemic sclerosis
- Sjögren syndrome
- Systemic lupus erythematous (SLE)
PRICES
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