Diagnostic Tests

CLINICAL ASSOCIATIONS

With uromodulin antibodies being detected in patients with diabetes mellitus type 2, Mitogen offers this assay to determine the levels of uromodulin. Patients with diabetes mellitus type 2 have significantly lower sUmod concentrations than non-diabetics.

Uromodulin is a kidney-specific glycoprotein whose function is speculated to be a regulator of ion transport and protection against urinary tract infection-causing bacteria as well as kidney stones. Though uromodulin is the most abundant protein in urine, it is also present in blood.