Systemic Lupus Erythematosus Panel
ANTIGENS / BIOMARKERS
Anti-Sm, U1RNP, Ro52/TRIM21, SSA/Ro60, SSB/La, PCNA, dsDNA, Ku, Ribosomal-P, Chromatin
TURNAROUND-TIME (TAT)
5-7 Days
SKU / TEST CODE
SLP
PROCEDURE / TECHNIQUE
ELISA, Line Immunoassay (LIA)
REFERENCE RANGE
Qualitative (SI :Signal Intensity) • Negative <10 SI • Weak Positive 11-29 SI • Medium Positive 30-89 SI • High positive >90 SI
SENSITIVITY / SPECIFICITY
TBD
CLINICAL ASSOCIATIONS
Mitogen’s Systemic Lupus Profile is a comprehensive autoimmune diagnostic test for systemic lupus erythematous (SLE). Some antigen targets such as anti-Sm in this test are SLE-specific, while others (i.e. anti-U1-RNP, anti-Ro60/SSA) can be seen in other systemic autoimmune disease.
Reference: M. Y. Choi and M. J. Fritzler. Autoantibodies in SLE: prediction and the p value matrix. Lupus. 28:1285-1291, 2019.
RELEVANT DISEASES
- ANCA-related vasculopathies / glomerulonephritis
- Anti-glutamate receptor encephalitis (type NMDA)
- Arthritis
- Arthritis (Juvenile arthritis / Juvenile idiopathic arthritis)
- Arthritis (Rheumatoid Arthritis)
- Asthma
- Autoimmune liver diseases
- Autoimmune mucocutaneous blistering diseases
- Autoimmune myositis / Autoimmune Inflammatory Myopathies
- Chorea
- Encephalitis
- Guillain-Barré syndrome
- Interstitial lung disease (ILD)
- Juvenile dermatomyositis (JDM)
- Limbic encephalitis (autoinflammatory)
- Lupus, Drug Induced Lupus (DIL)/ Drug-induced autoimmunity
- Lupus, Systemic lupus erythematous (SLE)
- Mixed connective tissue disease
- Multifocal motor neuropathy (MMN)
- Myasthenia gravis
- Myositis overlap syndromes
- Necrotizing myositis
- Primary Membranous nephropathy (pMN): aka primary membranous glomerulonephritis (pMGN) and idiopathic membranous nephropathy (IMN)
- Primary biliary cholangitis
- Rheumatoid Arthritis
- Scleroderma / systemic sclerosis
- Sjögren’s syndrome
- Systemic lupus erythematous (SLE)
- Thrombotic thrombocytopenia purpura (TTP)
- Transverse myelitis
- Vasculitis
PRICES
Health Providers & Labs |
Please inquire for pricing |
Direct to Customer / Patient |
Currently not available |
Other Tests To Consider
